### **Translation: The Chemical Level of Organization: Atomic and Molecular** --- ### **5.1 The Atom** #### **Definition** The atom is the smallest chemical component of our body. The 112 atomic elements are represented in the periodic table of elements. The atom is a basic unit that cannot be split by natural means. #### **Structure** - **Protons**: Positively charged particles forming the atomic nucleus along with neutrons. - **Neutrons**: Neutral particles responsible for isotopes (+ or - neutrons). - **Electrons**: Negatively charged particles forming the orbital around the nucleus. #### **Body’s Atomic Elements** Main elements in the body include: hydrogen, carbon, oxygen, nitrogen, sodium, potassium, phosphorus, calcium, chlorine, sulfur, etc. #### **Electrons** - In living tissues, only electrons are rearranged on electronic shells. - Electrons orbit the nucleus in approximate paths called orbitals. - The electron determines the atom’s chemical behavior, i.e., its bonding capability. #### **Atomic Bonds in Living Systems** Three main types of bonds: 1. **Ionic Bonds**: Electrons are transferred between atoms (oxidation-reduction). 2. **Covalent Bonds**: Two atoms share a pair of electrons. Polar covalent bonds have properties of both covalent and ionic bonds due to unequal electron sharing. 3. **Hydrogen Bonds**: Common in biological molecules, such as between complementary nucleotides in DNA. These bonds are weak interactions involving hydrogen bonded to oxygen or nitrogen attracted to another electronegative atom. --- ### **5.2 The Molecule** Molecules are composed of atoms. They group together through covalent, ionic, or hydrogen bonds to form the four essential macromolecules for life: proteins, carbohydrates, lipids, and nucleic acids. --- #### **Proteins (Protides)** - **Overview**: Generic term for nitrogen-containing organic substances such as amino acids, peptides, polypeptides, proteins, enzymes, and cellular receptors. Proteins are made up of 20-22 amino acids, each containing a nitrogen atom. - **Functions**: - Structural support (collagen, elastin, keratin). - Transport (hemoglobin). - Communication (hormones, neurotransmitters). - Movement (myosin-actin). - Defense (antibodies). - Catalysis (enzymes). - Storage (e.g., ferritin for iron). --- #### **Carbohydrates** - **Overview**: Known as hydrates of carbon, including sugars, fruits, and grains. Soluble in water and composed of carbon, hydrogen, and oxygen atoms. - **Structure**: 1. **Monosaccharides**: Simple sugars (e.g., glucose, fructose, galactose). 2. **Disaccharides**: Combinations of two monosaccharides (e.g., sucrose, lactose, maltose). 3. **Polysaccharides**: Long chains of monosaccharides forming macromolecules (e.g., glycogen, starch, cellulose). - **Functions**: Primary source of readily available energy for cells. --- #### **Lipids** - **Overview**: Fats and fat-like substances insoluble in water, including triglycerides, phospholipids, and steroids. - **Functions**: - Energy storage. - Cushioning and protecting organs. - Thermal insulation. - **Structure**: 1. **Triglycerides**: Composed of glycerol and fatty acids. 2. **Phospholipids**: Hydrophobic tails (fatty acids) and hydrophilic heads (phosphate group). 3. **Steroids**: Include cholesterol, hormones, and vitamin D precursors. --- #### **Nucleic Acids** - **Overview**: Store genetic information and participate in cellular energy transfer and messaging (e.g., DNA and RNA). - **Structure**: Built from nucleotides, which consist of a sugar, a phosphate group, and a nitrogenous base. 1. **DNA (Deoxyribonucleic Acid)**: - Double-helix structure with complementary base pairing (A-T, G-C). - Stores genetic instructions for replication and cellular function. 2. **RNA (Ribonucleic Acid)**: - Single-stranded and includes uracil instead of thymine (A-U, G-C). - Transcribes and translates DNA instructions for protein synthesis. 3. **ATP (Adenosine Triphosphate)**: - Composed of adenine, ribose, and three phosphate groups. - Stores and releases energy for cellular processes. ---